Fig. 3. Localization and uptake pathways of coumarin-6-loaded Se@β-CD-FA@PTX in MCF-7 cells. (A) The cells were treated with coumarin-6-loaded Se@β-CD-FA@PTX for different periods of time and were observed under a fluorescence microscope, stained with LysoTracker (red fluorescence, lysosome) and DAPI (blue fluorescence, nucleus) (magnification, 100×). (B) Intracellular uptake of Se@β-CD-FA@PTX in MCF-7 cells with different endocytosis-inhibited conditions. Significant difference between the treatment and control groups is indicated at the P < 0.05 (*) or P < 0.01 (**) level.
