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. 2022 May 10;13:2563. doi: 10.1038/s41467-022-30190-1

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Type A, a truncated HPV genome containing E6/E7. b Type B, a truncated HPV genome lacking E6/E7. c Type C, an overflowing continuous segment containing the intact HPV genome. d Type D, a combination of Type A, Type B, or Type C. In each panel, the two dashed arrows on the top indicate the HPV DNA fragment that was integrated into the human genome; the light blue and orange boxes on the bottom represent the human genome and virus genome, respectively. Source data are provided as a Source Data file.