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. 2022 May 10;13:2555. doi: 10.1038/s41467-022-29968-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a–d Co-occurrence networks of CAGs (co-abundance groups) before and after intervention in different groups (a: AED: n = 20; b: AEx: n = 20; c Diet : n = 21; d: NI: n = 15). The nodes represent CAGs and the edges represent statistically significant differences (p < 0.05) via Spearman correlation between CAGs without adjustment. The style of the edge is set to a dashed line and a solid line, which represent negative and positive correlation, respectively. Gray edges indicate correlation before intervention; colored edges indicate correlation after intervention. e Network connection properties. f Network robustness test.