TABLE 1.
Clinical characteristics of heart transplant patients divided in NACR and PACR.
| Characteristics | NACR (n = 36) | PACR (n = 31) | p-value |
| Age (years) | 49.33 ± 12 | 55.19 ± 7.8 | 0.03 |
| Gender female/male | 25/11 | 15/16 | 0.08 |
| SBP (mmHg) | 129.17 ± 21 | 137.74 ± 26 | 0.14 |
| DBP (mmHg) | 83.67 ± 17 | 88.10 ± 16 | 0.29 |
| HR (bpm) | 84.78 ± 15 | 88.19 ± 13 | 0.32 |
| Heigh (cm) | 164.31 ± 7 | 163.90 ± 7 | 0.82 |
| Weight (kg) | 62.03 ± 10 | 65.51 ± 12 | 0.2 |
| BSA (m2) | 1.67 ± 0.2 | 1.71 ± 0.2 | 0.35 |
| BMI (cm2/kg) | 22.97 ± 3.6 | 24.40 ± 4 | 0.13 |
| Time HT to EMB <6 m/>6 m | 28/8 | 27/4 | 0.87 |
| Hypertension | |||
| Diabetes | |||
| Primary heart disease | 0.57 | ||
| Chagas cardiomyopathy | 19 (53%) | 23 (74%) | |
| Idiopathic dilated cardiomyopathy | 6 (18%) | 4 (13%) | |
| Ischemic cardiomyopathy | 3 (8%) | 3 (10%) | |
| Valvular cardiomyopathy | 2 (6%) | 0 | |
| Congenital cardiomyopathy | 1 (3%) | 0 | |
| Postpartum cardiomyopathy | 2 (6%) | 0 | |
| Non compaction cardiomyopathy | 1 (3%) | 11 (3%) | |
| CTRCD | 1 (3%) | 0 | |
| Imunossupressor drugs | |||
| Corticosteroids | 34 (94%) | 28 (90%) | 0.52 |
| Mycophenolate mofetil | 25 (69%) | 15 (48%) | 0.08 |
| Tacrolimus | 26 (72%) | 11 (35%) | 0.003 |
| Cyclosporine | 10 (28%) | 20 (64%) | 0.003 |
| Azathioprine | 11 (30%) | 16 (52%) | 0.08 |
| Time frame from HT to EMB (days) | 89 ± 95 | 95 ± 98 | 0.52 |
NACR, negative acute cellular rejection; PACR, positive acute cellular rejection; SBP, systolic blood pressure; DBP, diastolic blood pressure; HR, heart rate; BSA, body surface area; BMI, body mass index; HT, heart transplant; EMB, endomyocardial biopsy; CTRCD, cancer-therapeutic-related cardiac dysfunction.