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. 2022 Jan 16;17(2):206–218. doi: 10.1016/j.ajps.2021.12.003

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© 2022 Shenyang Pharmaceutical University. Published by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig 3 — Synergistic cytotoxicity of TPL+Ce6/NPs in HepG2 and B16 cells for 48 h treatment. Cytotoxicity of TPL+Ce6/NPs, containing 20 nM TPL and 54 nM Ce6 equivalently, against HepG2 cells (A) and B16 cells (C) with laser irradiation after 48-h treatments. Comparison of cytotoxicity between different groups with laser or without laser irradiation in HepG2 cells (B) and B16 cells (D). Relative ROS generation of cells after various treatments by FCM analysis (E). The produced ROS amounts in different groups (F). *P < 0.05 indicates a statistically significant difference between groups.