Fig. 8.

(A) Schematic illustration showing in situ self-generation of Cu²⁺ for MR imaging. (B) T₁₋MR imaging of CP NCs solution with different concentrations in absence or presence of 100 µM H₂O₂. In vivo T₁₋MRI (C), PAI (D) and PTI (E) of tumor-bearing mice. Reproduced from [76]. Copyright 2019 John Wiley & Sons. (F) Fluorescence images of 4T1 tumor-bearing mice by intravenous injection of Cy5.5-labeled nanocages. PAI (G) and CT imaging (H) of 4T1 tumor-bearing mice. Reproduced from [87]. Copyright 2020 John Wiley & Sons. (I) PET imaging of tumor-bearing mice after intravenous injection with the ⁶⁴Cu-labeled nanoreactor. (J) Fluorescence images of tumor-bearing mice after intravenous injection with the nanoreactor. Reproduced from [55]. Copyright 2020 John Wiley & Sons.