Table 2.
Independent associations between urinary levels of AP and CP/LP activation fragments and terminal pathway C5a
| Standardized β | P | |
|---|---|---|
| Focal and segmental glomerulosclerosis, r2: 0.52 | ||
| Ba | 0.59 | 0.003 |
| C4a | 0.36 | 0.047 |
| Membranous nephropathy, r2: 0.86 | ||
| Ba | 0.67 | <0.001 |
| C4a | 0.48 | <0.001 |
| IgA nephropathy, r2: 0.89 | ||
| Ba | 0.73 | <0.001 |
| C4a | 0.31 | <0.001 |
| Lupus nephritis, r2: 0.83 | ||
| Ba | 0.72 | <0.001 |
| C4a | 0.35 | 0.009 |
| ANCA-associated vasculitis, r2: 0.71 | ||
| Ba | 0.21 | 0.13 |
| C4a | 0.77 | <0.001 |
ANCA, antineutrophil cytoplasmic autoantibody; AP, alternative pathway; CP, classical pathway; LP, lectin pathway.
C4a and Ba correspond to CP/LP and AP activation fragments, respectively.