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. 2022 Apr 27;13:848715. doi: 10.3389/fendo.2022.848715

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Copyright © 2022 Yuan, Chen, Zhang, Lin and Yang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential biomarkers in HUA and Con subjects by LefSe analysis (α value = 0.05, logarithmic LDA score threshold = 2.0). HUA, hyperuricemia; Con, control. In the LEFse tree, different colors indicate different groups. Note colored in a group color shows an important microbe biomarker in the group and the biomark name will list in the upper right corner. The yellow notes represent the biomarker which do not show any importance in groups. (A) LDA plot of the differential bacterial by LEfSe analysis; (B) clodagram of the differential bacteria lby LEfSe analysis.