Table 2.

Results of correlation analysis using Pearson’s test for renal apoptosis index in addition to the relative mRNA and protein expression of Casp-3 with the serum and urine concentrations of biochemical parameters at euthanasia (week-9 post treatment).

	Apoptosis index (%)	Relative Casp-3 mRNA expression	Relative Casp-3 protein expression
Fasting blood glucose (mmol/L)	0.857*	0.849*	0.883*
Serum insulin (μU/mL)	−0.760*	−0.663*	−0.822*
Total Cholesterol (mmol/L)	0.856*	0.800*	0.878*
LDL (mmol/L)	0.886*	0.811*	0.927*
HDL (mmol/L)	−0.797*	−0.681*	−0.847*
Triglycerides (mmol/L)	0.915*	0.797*	0.917*
Serum creatinine (mg/dL)	0.723*	0.765*	0.705*
Serum urea (mg/dL)	0.805*	0.695*	0.824*
Serum total protein (g/dL)	−0.753*	−0.604*	−0.801*
24hr Urine volume (ml)	0.921*	0.816*	0.931*
24hr urine creatinine (mg/dL)	−0.767*	−0.692*	−0.728*
24hr Creatinine clearance (mL/min)	−0.739*	−0.602*	−0.724*
24hr urine total protein (g/dL)	0.937*	0.786*	0.923*

* = P < 0.0001.