TABLE 2.

Pulmonary evaluation and laboratory tests at the 3‐month follow‐up

	All	D _LCO ≥ 60% predicted	D _LCO < 60% predicted
	N = 87	N = 61	N = 26	p‐value	N
Pulmonary function
D _LCO (% predicted)	66.1 [57.1;73.9]	71.4 [65.6;77.0]	52.8 [47.1;55.9]	<0.001	87
D _LCO				<0.001	87
< 60% predicted	26 (29.9%)	0 (0.00%)	26 (100%)
< 80% predicted	50 (57.5%)	50 (82.0%)	0 (0.00%)
≥80% predicted	11 (12.6%)	11 (18.0%)	0 (0.00%)
6‐min walking test
Distance (m)	400 [365;430]	410 [390;448]	378 [305;404]	0.001	84
Oxygen saturation average (%)	96.0 [94.0;97.0]	96.0 [95.0;97.0]	95.0 [94.0;96.0]	0.009	85
Oxygen saturation initial (%)	97.0 [96.0;97.0]	97.0 [96.0;97.0]	96.0 [95.2;97.0]	0.005	85
Oxygen saturation final (%)	96.0 [95.0;97.0]	96.0 [95.0;97.0]	96.0 [94.0;96.0]	0.003	85
Oxygen saturation minimal (%)	95.0 [93.0;96.0]	95.0 [93.0;96.0]	94.0 [92.0;95.0]	0.017	85
Chest CT
Lesions
Reticular	42 (48.8%)	29 (48.3%)	13 (50.0%)	1.000	86
Fibrotic	20 (23.3%)	10 (16.7%)	10 (38.5%)	0.055	86
TSS score	5.00 [2.00;7.00]	2.50 [1.00;7.00]	8.00 [5.00;11.8]	<0.001	86
Laboratory tests
Creatinine (mg/dl)	0.82 [0.72;0.95]	0.81 [0.71;0.91]	0.90 [0.74;1.03]	0.126	87
Glomerular filtrate (ml/min/1.73m²)	90.0 [83.3;90.0]	90.0 [89.4;90.0]	88.2 [74.7;90.0]	0.011	87
C‐reactive protein (mg/L)	2.40 [2.00;4.55]	2.50 [2.00;4.70]	2.20 [2.00;4.20]	0.602	87
Leucocyte count (x10⁹/l)	6.49 [5.60;7.56]	6.44 [5.73;7.36]	7.11 [5.44;8.35]	0.756	87
Neutrophil count (x10⁹/L)	3.40 [2.60;4.00]	3.53 [2.59;3.94]	3.22 [2.66;4.67]	0.770	87
Lymphocyte count (x10⁹/L)	2.12 [1.79;2.79]	2.26 [1.81;2.76]	2.08 [1.71;2.88]	0.610	87
Monocyte count (x10⁹/L)	0.54 [0.45;0.68]	0.51 [0.45;0.65]	0.59 [0.48;0.70]	0.161	87
Platelet count (x10⁹/L)	241 [210;277]	243 [217;277]	240 [197;272]	0.433	87
Urea (mg/dL)	38.0 [33.0;45.0]	37.0 [33.0;44.0]	39.0 [35.0;49.5]	0.188	87

Abbreviations: D _LCO: carbon monoxide diffusing capacity; TSS: total severity score.

^{^a}

Continuous variables are expressed as median [P25;P75].

^{^b}

Categorical variables are expressed as n (%).