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. Author manuscript; available in PMC: 2022 Oct 8.
Published in final edited form as: Science. 2022 Apr 8;376(6589):eabg5601. doi: 10.1126/science.abg5601

FIG. 3.

FIG. 3.

Categories of mutation events exhibit different mutation patterns. Positional clustering of mutations (y-axis, percentage of maximum) is plotted against genomic positions (x-axis) around mutation events that fall into regulatory regions [(A), orange] or overlap with tissue-specific genes [(B), teal]. Genomic boundaries of the closest gene are marked at the bottom of each plot, and white arrowheads mark the direction of its transcription.