Table 1.

Double controlled studies of SSc ILD treatment with RTX.

Author	No. of patients	Disease type	RTX scheme	Follow-up months	Outcome
Daoussis et al. 2010	8	SSc serious ILD RTX add on Tx vs standardTX	Lymphoma scheme	12	Improvement of PFTS compared to controls; steady HRCT lesions
Jordan et al. 2015	25	SSc ILD RTX +stand vs standard Tx	RA scheme	6	Decline in FVC/stable DLCO
Daoussis et al. 2017	51	SscILD RTX add onTx Vs standard Tx	Lymphoma scheme	48	FVC increase/stable DLCO
Boonstra M et al. 2017	16	SscILD	RA scheme	24	Stable PFTs and HRCT lesions
Thiebeau et al. 2018	13	Progressive Ssc ILD	RA scheme	24	No difference compared to control/improvement of PFTs in RTX group
Sircar et al 2018	25	SSc ILD RTXvs CYC	RA scheme	6	Improved FVC compared to CYC
M Elhai, M Boubaya et al. 2019 EUSTAR	146 patients	SSc ILD	RA scheme	24	Stable PFTs