Table 3.
Pathway and biological process enrichment analysis of KIF20A and top 20 interacting proteins.
| GO | Category | Description | Count | -Log10(P) |
|---|---|---|---|---|
| GO:0007051 | GO Biological Processes | spindle organization | 11 | 19.88 |
| R-HSA-1640170 | Reactome Gene Sets | Cell Cycle | 14 | 18.02 |
| M129 | Canonical Pathways | PID PLK1 PATHWAY | 8 | 17.52 |
| M242 | Canonical Pathways | PID AURORA A PATHWAY | 7 | 16.18 |
| R-HSA-69620 | Reactome Gene Sets | Cell Cycle Checkpoints | 9 | 12.75 |
| R-HSA-3108232 | Reactome Gene Sets | SUMO E3 ligases SUMOylate target proteins | 7 | 10.56 |
| R-HSA-6804756 | Reactome Gene Sets | Regulation of TP53 Activity through Phosphorylation | 6 | 10.45 |
| WP1984 | WikiPathways | Integrated breast cancer pathway | 6 | 9.07 |
| GO:0060236 | GO Biological Processes | regulation of mitotic spindle organization | 4 | 7.86 |
| GO:0030162 | GO Biological Processes | regulation of proteolysis | 8 | 7.7 |
| GO:0090307 | GO Biological Processes | mitotic spindle assembly | 4 | 7.52 |
| GO:1903800 | GO Biological Processes | positive regulation of production of miRNAs involved in gene silencing by miRNA | 3 | 7.2 |
| GO:0051347 | GO Biological Processes | positive regulation of transferase activity | 7 | 7.18 |
| GO:0010639 | GO Biological Processes | negative regulation of organelle organization | 4 | 4.12 |