Table 1.
Baseline characteristics of patients.
| Group | Basal Insulin Group (N=199) |
Premixed Insulin Group (N=194) |
p value |
|---|---|---|---|
| Sex (M/F) | 125/74 | 113/81 | 0.83 |
| Age (years) | 59.40 ± 11.88 | 63.14 ± 9.51 | 0.68 |
| HbA1c (%) | 7.90 ± 1.69 | 7.69 ± 1.43 | 0.33 |
| BMI (kg/m2) | 24.92 ± 4.56 | 24.82 ± 3.10 | 0.61 |
| Duration of T2DM (years) | 15.0 (10.00, 16.50) | 13.00 (9.00, 20.00) | 0.51 |
| Duration of insulin (years) | 5.23 (3.00, 7.71) | 6.42 (5.57, 11.00) | <0.01** |
| Insulin dose (IU/kg/day) | 0.30 ± 0.10 | 0.53 ± 0.17 | <0.01** |
| Fasting C-peptide (ng/ml) | 1.20 ± 1.00 | 1.38 ± 0.99 | 0.07 |
| Ins-Ab (COI) | 4.69 (1.91, 10.02) | 10.57 (3.95, 28.07) | <0.01** |
Data was shown as mean ± SD or median (first quartile, third quartile). M, male; F, female; HbA1c, glycated haemoglobin; BMI, body mass index; **p < 0.01. Ins-Ab, insulin antibody; COI, OD/CO; OD, absorbance; CO, average absorbance of negative control; The reference range of normal values for antibody is <1 COI.