Table 4.

Clinical characteristics of patients with different HbA1c levels.

Group	HbA1c<7%			7%≤HbA1c≤9%			HbA1c>9%
	Basal Insulin (N=69)	Premixed Insulin (N=68)	P value	Basal Insulin (N=80)	Premixed Insulin (N=93)	P value	Basal Insulin (N=50)	Premixed Insulin (N=33)	P value
MBG (mmol/L)	7.54±1.57	7.15±1.51	<0.01**	9.62±2.40	9.28±2.21	0.412	10.53±2.43	11.58±3.50	0.211
MAGE (mmol/L)	4.72±2.53	5.36±2.09	0.035*	5.43±2.48	6.33±2.13	0.011*	5.78±2.88	6.28±3.10	0.389
SD (mmol/L)	1.82±0.78	2.54±0.77	<0.01**	2.28±0.84	3.04±0.95	<0.01**	2.46±0.98	2.85±1.22	0.182
CV (%)	22.87±9.03	36.08±9.77	<0.01**	24.25±9.61	33.35±8.70	<0.01**	23.43±8.59	24.62±9.18	0.612
TIR (%)	86.46 (72.05, 96.35)	73.96 (61.28, 80.90)	<0.01**	64.76 (36.63, 86.72	60.76 (43.58, 75.87)	0.287	48.78 (19.53, 74.83)	37.84 (19.44, 59.20)	0.235
TBR <3.9 mmol/L (%)	0.00 (0.00, 0.35)	9.38 (1.04, 18.06)	<0.01**	0.00 (0.00, 0.00)	1.04 (0.00, 7.29)	<0.01**	0.00 (0.00, 0.00)	0.00 (0.00, 0.00)	0.508
TBR <3.0 mmol/L (%)	0.00 (0.00, 0.00)	1.74 (0.00, 7.38)	<0.01**	0.00 (0.00, 0.00)	0.00 (0.00, 2.43)	<0.01**	0.00 (0.00, 0.00)	0.00 (0.00, 0.00)	0.321
C-Peptide (ng/ml)	1.22±0.83	1.32±0.73	0.53	1.36±0.38	1.47±1.13	0.58	1.05±1.82	1.32±1.22	0.27
Ins-Ab (COI)	3.10 (1.13, 11.06)	9.25 (2.89, 29.74)	<0.01**	5.06 (2.37, 10.09)	13.43 (5.53, 30.31)	<0.01**	4.31 (1.98, 9.14)	8.42 (2.68, 13.98)	0.13

Data was shown as mean ± SD or median (first quartile, third quartile). *p < 0.05, **p < 0.01. HbA1c, glycated haemoglobin; MBG, 24-hour mean blood glucose; GV, Glycaemic variability; MAGE, 24-hour mean amplitude of glycaemic excursion; SD, Standard deviation of blood glucose; CV, coefficient of variation; TIR, time in range (3.9-10 mmol/L); TAR, time above target range (>13.9 mmol/L); TBR, time-below-target ranges (<3.9 mmol/L or <3.0 mmol/L); Ins-Ab, insulin antibody; COI, OD/CO; OD, absorbance; CO, average absorbance of negative control; The reference range of normal values for antibody is <1 COI.