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. Author manuscript; available in PMC: 2022 May 11.
Published in final edited form as: J Food Prot. 2021 Dec 1;84(12):2195–2212. doi: 10.4315/JFP-21-219

Table 3.

Summary of key data on the occurrence of ethyl carbamate in alcoholic beverages.a

Beverage Concentration mean (µg/kg)b Concentration range (µg/kg)b n Analytical methods Country/region References
Beer 1.7c ND–20 232 GC-MS China; Hong Kong Tang et al. (2011); Li et al. (2017)
Distilled spirits 44c ND–390 904 GC/N-TEA; LC-FLD; GC-MS China; Mexico; Germany; Guatemala; US Diachenko et al. (1992); Madrera et al. (2009); Liu et al. (2013); Liu et al. (2011); Wu et al. (2012); Lachenmeier et al. (2009)
Fruit brandy 1,000c 3.5–5,100 103 GC/N-TEA; GC-MS Denmark; Korea; US Diachenko et al. (1992); Vahl et al. (1993); Ha et al. (2006)
Stone fruit spirits 1,400 10–18,000 631 GC-MS Germany Lachenmeier (2005)
Sugar cane spirits/cachaça 110c 12–910 385 GC-MS; HPLC-FLD Brazil Nobrega et al. (2011); d’Avila et al. (2016);
Bortoletto & Alcarde (2015); Masson et al. (2014)
Wine, fortified 55c ND–260 248 GC/N-TEA; GC-MS; LC-MS Denmark; US; Various from FAO submission; UK; Portugal; South Africa Diachenko et al. (1992); Vahl et al. (1993)
FAO (2006); Hasnip et al. (2007); Perestreloa et al. (2010); Alberts et al. (2011)
Wine, table 9.0c ND–61 5,930 GC/N-TEA; GC-MS; LC-MS Denmark; China; Spain, South Africa; US; Various from FAO submission Diachenko et al. (1992); Vahl et al. (1993); FAO (2006); Wu et al. (2012); Fu et al. (2016); Jagerdeo et al. (2002); Uthurry et al. (2004); Alberts et al. (2011)
Yellow rice wine 150 ND–580 221 GC-MS; HPLC-FLD China Mo et al. (2014); Fu et al. (2010)
a

Abbreviations used: FAO, Food and Agriculture Organization; GC-MS, gas chromatography-mass spectrometry; GC/N-TEA, gas chromatography-thermal energy analyzer with nitrogen converter; LC-MS, liquid chromatography-mass spectrometry; LC-FLD, liquid chromatography-fluorescence detection; ND, not detected.

a

Ethyl carbamate data rounded to two significant figures.

*

Mean of means from reference data shown for display purposes in table.