Table 2.

Change (T2 − T1) in thrombin generation and its sensitivity to APC or TM, stratified by use of tamoxifen and AIs

	Tamoxifen (n=42)				Aromatase inhibitors (n=65)
	T1 mean (SD)	T2 mean (SD)	Absolute difference (95% CI)	P	T1 mean (SD)	T2 mean (SD)	Absolute difference (95% CI)	P
ETP, nM × min	1596.8 (298.5)	1683.0 (297.8)	+86.2 (+30.3 to +142.2)	.003	1531.3 (252.7)	1575.7 (233.2)	+44.4 (−4.2 to +93.1)	.07
Thrombin peak, nM	235.4 (65.8)	268.3 (62.5)	+32.9 (+21.1 to +44.7)	<.001	207.2 (48.4)	214.4 (47.2)	+7.2 (−2.5 to +16.9)	.13
nAPCsr	0.86 (0.19)	0.97 (0.19)	+0.11 (+0.06 to +0.16)	<.001	0.84 (0.19)	0.84 (0.19)	0.0 (−0.05 to + 0.05)	.91
nTMsr	0.81 (0.35)	1.07 (0.36)	+0.26 (+0.19 to +0.33)	<.001	0.58 (0.28)	0.60 (0.27)	+0.02 (−0.03 to + 0.07)	.37