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. 2022 Apr 25;12:342–354. doi: 10.1016/j.ibneur.2022.04.008

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© 2022 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 5 — Effects of neonatal manipulations on D2 receptors labelled with [³H] raclopride in basal ganglia nuclei of adolescent and adult male rats. Bar graphs depict specific [³H] raclopride binding levels in brain regions of male adolescent (P39–41) and adult (P113–115) control, BMS and PMS rats. Data are presented as mean ± SEM of specific binding expressed in fmol/mg tissue (n = 6–8 adolescent and 8–10 adult rats/group). # Statistically significant manipulation x age interaction (P < 0.05); § statistically significant age effect (P < 0.001; two-way ANOVA with manipulation and age as independent factors). C: control; BMS: brief maternally separated; PMS: prolonged maternally separated rats. CPu: caudate-putamen; NAcC: nucleus accumbens core; NAcS: nucleus accumbens shell. * P < 0.05; * *P < 0.01.