Table 4.
Sepsis Comparison of NfL plasma concentration levels between patients who did not have a diagnosis of sepsis on admission and those who did have a diagnosis of sepsis on admission.
| No Sepsis N | Sepsis N | p-value | |||
|---|---|---|---|---|---|
| Concentration day 11 | 101 | 76.5 (79.0) | 40 | 120.8 (140.2) | 0.0042 |
| Concentration day 31 | 92 | 100.8 (100.2) | 32 | 221.2 (342.1) | 0.0102 |
| Concentration ratio day 3 to day 1 | 92 | 1.8 (1.3) | 32 | 1.5 (0.5) | 0.7043 |
1 based on a linear mixed model with log concentration as the outcome and fixed effect for delirium/deep sedation and day (1 or 3) and the interaction between delirium/deep sedation and day with a random effect for the participant including data from day 1 and day 3.
2p-value is the marginal contrast at day 1 and day 3 respectively.
3based on the interaction between delirium/deep sedation and day