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Graphic representation of the cell culture models hosted in the organs-on-a-chip involved in ADME. The scheme highlights the main cell types that should be included into the most advanced state-of-the art microfluidic devices for drug screening. The solid arrows point out the direction of diffusion of drug and/or its metabolite. The dashed arrows indicate the fate of orally administered drug in the human body. Created with BioRender.com.
