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. 2022 May 10;22:146. doi: 10.1186/s12905-022-01737-7

Table 2.

Endometriosis-associated pain symptoms intergroup comparison at baseline and at 3, 6 and 12 months of women on 24/4 regimen 17β-estradiol (1.5 mg) and Nomegestrol Acetate (2.5 mg) (E2/NOMAC) combined oral contraceptive, or on Dienogest (DNG) 2 mg daily

Pain symptoms Baseline 3rd month 6th month 12th month
95% CI P* 95% CI P* 95% CI P* 95% CI P*
Chronic Pelvic Pain − 0.06 to 1.06 0.08 − 0.82 to 0.02 0.06 0.13 to 1.26 0.01 − 0.02 to 0.82 0.06
Dysmenorrhea − 4.61 to 1.01 0.2 − 0.48 to 2.88 0.1 0.32 to 4.47 0.02 − 0.6 to 2.8 0.2
Dyspareunia − 4.51 to 1.11 0.12 − 1.35 to 5.95 0.2 1.12 to 5.27 0.003 − 0.96 to 2.96 0.2

*t = two-sided t test; CI = Confidence interval