Table 2.

Summary of attributes of HPV-related Cervical cancer, OPSCC and Sinonasal carcinoma.

	Cervical cancer	OPSCC	Sinonasal carcinoma
Histopathology	Keratinizing SCC, AC, large cell nonkeratinizing, small cell nonkeratinizing neuroendocrine	Non-keratinizing SCC with basaloid morphology	Squamoid, ductal myoepithelial non- or partially-keratinizing, papillary, adenosquamous,basaloid, small cell
Molecular diagnosis	HPV-DNA testing p16 immunohistochemistry	p16 immunohistochemistry (and HPV-DNA)	Not recommended
Early-stage primary treatment	Surgery	Surgery and/or RT	Surgery and/or RT
Treatment sensitivity to chemotherapy and radiation	Moderate	High	High