Fig. 1.

Low expression of integrin αV in breast cancer tissues is linked to poor prognosis. Patients were stratified according to the expression of integrin αV: H-score under mean (= 10.34) was considered low (n=242, red) and H-score above mean, high (n=92, blue). A) Although the expression of integrin αV has not shown relevance for Overall Survival (OS) (p=0.081), cancer specific survival (CSS) (B) showed statistically significant differences pointing out that the decrease in integrin αV expression correlates with a worse prognosis (p=0.041). The expression of integrin αV did not show statistically significant relationships for both C) Disease-free survival (DFS) (p=0.347) and D) Distant disease-free survival (DDFS) (p=0.268).