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. 2022 Mar 10;29(6):1106–1119. doi: 10.1093/jamia/ocac031

Table 2.

Frequency of main study characteristics

Count (%)a
Publication year 2016–2020 43 (49%)
2011–2015 34 (39%)
2005–2010 11 (12%)
Quality appraisal (4* being lowest risk of bias) 4* 4 (4%)
3* 37 (42%)
2* 33 (38%)
1* 14 (16%)
Study type Randomized controlled trial 21 (24%)
Nonrandomized controlled trial 3 (3%)
Cohort study 5 (6%)
Before and after study 8 (9%)
Cross sectional study 3 (3%)
Other quantitative study 11 (12%)
Qualitative study 27 (31%)
Mixed methods study 10 (11%)
Continent North America 57 (65%)
Europe 26 (30%)
Asia 4 (4%)
Australia 1 (1%)
Setting Hospital care (including secondary and tertiary settings) 51 (58%)
Outpatient care (including specialty and primary care settings) 36 (41%)
Nursing home 1 (1%)
Specialty area Medication safety 19 (22%)
Diabetes 17 (19%)
Cardiovascular 15 (17%)
Respiratory 6 (7%)
Oncology 9 (10%)
Nephrology 2 (2%)
Geriatrics 4 (4%)
General medicine 4 (4%)
Infectious disease 11 (12%)
Surgery 5 (6%)
Obstetrics 1 (1%)
Pediatrics 3 (3%)
Radiology 4 (4%)
Psychiatry (including substance misuse) 5 (6%)
a

Counts may add to more than 100% where papers are in multiple categories.