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. 2022 Apr 21;13(18):5345–5352. doi: 10.1039/d2sc01672a

Fig. 1. (a) Chemical structure of the photocleavable linker in the PARC. (b) IEC analysis of αPD-L1, PARC, or PARC irradiated with 365 nm light (10 mW cm−2) for 5 min. (c) Normalized fluorescence of PD-L1-positive or -negative HCT116 cells treated with αPD-L1 or PARC (0–1000 nM) and a fluorescent secondary antibody. (d) siPD-L1 release profiles of PARC irradiated with 365 nm light (10 mW cm−2) for 1–6 min. (e) SDS-PAGE analysis of αPD-L1 and PARC without or with irradiation with 365 nm light (10 mW cm−2) for 5 min. Data are shown as mean ± SD (n = 3).

Fig. 1