Table 2.
Summary of studies on social cognition in the behavioural variant frontotemporal dementia.
| References | Design | Patients (N) | Mean age of patients (S.D) | HC (N) | Mean age of HC (S.D) | SC domains | Assessment tools | Results | JBI |
|---|---|---|---|---|---|---|---|---|---|
| Torralva et al. (2009) | C-S | 35 | G1: 65 (7.4), G2: 69.1(5.7) | 14 | 65.5 (6.5) | ToM | RMET, FPT | Patients impaired in ToM | G |
| Grossman et al. (2010) | C-S | 19 | 62.38 (12.30) | 19 | 72.55 (6.85) | ToM | Ad-hoc test | Patients impaired in ToM | M |
| Baez et al. (2014) | C-S | 37 | 66.0 (7.43) | 30 | 55 (8.64) | ToM, EP | TASIT, RMET, EPT, SNQ | Patients impaired in EP | G |
| Cerami et al. (2014) | C-S | 18 | 63.36 (7.47) | 36 | 62.83 (7.95) | ToM, EP, AB | Ad-hoc test | Patients impaired in AB | M |
| Savage et al. (2014) | C-S | 54 | 62.5 (9.9) | 30 | 63.4 (4.2) | EP | TASIT, EDT | Patients impaired in EP | G |
| Cerami et al. (2015) | C-S | 17 | 67.88 (9.92) | N/A | N/A | EP | E60, SET, IRI | Patients impaired in EP | G |
| Custodio et al. (2015) | C-S | 28 | 65.15 (2.95) | 20 | 66.4 (3.9) | ToM | FBT, RMET | Patients impaired in ToM | G |
| Oliver et al. (2015) | C-S | 24 | 64.7 (7.9) | 24 | 65 (8.5) | EP | IRI; MET | Patients impaired in EP | G |
| Torralva et al. (2015) | C-S | 14 | 69.9 (8.5) | 18 | 64.5 (6.4) | ToM | RMET, FPT | Patients impaired in ToM | G |
| Van den Stock et al. (2015) | C-S | 20 | 65.7 (8.7) | 22 | 66.6 (6.1) | EP | Ad-hoc test | Patients impaired in EP | G |
| Baez et al. (2016b) | C-S | 21 | 63.80 (7.33) | 19 | 60.42 (6.77) | AB | Ad-hoc test | Patients impaired in AB | G |
| Jastorff et al. (2016) | C-S | 14 | 67.2 (8.4) | 19 | 66.5 (6.3) | EP | Ad-hoc test | Patients impaired in EP | G |
| Sedeno et al. (2016) | C-S | 14 | 66.42 (6.83) | 12 | 62.58 (6.30) | ToM | TASIT; RMET | Patients impaired in ToM | G |
| Tabernero and Politis (2016) | C-S | 26 | 68.0 (7.0) | 23 | 68.0 (7.0) | EP, ToM | E60, FPT, RMET | Patients impaired in all domains | M |
| Tabernero et al. (2017) | C-S | 26 | 67.42 (6.41) | 30 | 69.97 (8.2) | EP, ToM | RMET, FPT, IGT | Patients impaired in all domains | M |
| Van den Stock et al. (2017) | C-S | 13 | 66.6 (7.22) | 19 | 66.5 (6.28) | EP, SP, AB | Ad-hoc test, RMET | Patients impaired in all domains | G |
| Gossink et al. (2018) | Lo | 22 | 62.8 (6.7) | N/A | N/A | EP, ToM | E60, FPT | bvFTD more impaired than other ND | M |
| Reus et al. (2018) | Lo | 34 | 63.2 (6.7) | N/A | N/A | EP, ToM | E60, FPT | No change over time in EP or ToM | G |
| Schroeter et al. (2018) | C-S | 86 | 63.9 (9.6) | 43 | 66.1 (10.1) | ToM | RMET | Patients impaired in ToM | G |
| Giovagnoli et al. (2019) | C-S | 14 | 56.79 (14.92) | 14 | 56.57 (12.05) | ToM | FPT | Patients impaired in ToM | G |
| Van den Stock et al. (2019) | C-S | 15 | 67.3 (6.65) | 19 | 66.6 (6.45) | ToM | FH | Patients impaired in ToM | G |
| Kawano et al. (2020) | C-S | 23 | 60 (7) | 30 | 59 (8) | EP | Ekman | Patients impaired in EP | M |
| Lillo et al. (2020) | C-S | 20 | 61.5 (6.3) | 21 | 59.2 (8.8) | ToM, EP | Mini-SEA | Patients impaired in EP and ToM | M |
AB, Attribution Bias; ADFES, Amsterdam Dynamic Facial Expression Set; CATS, Affect Matching subtest of the Comprehensive Affect Testing System; C-S, Cross-sectional; EDT, Emotion Detection task; E60, Ekman60; EP, Emotional Processing; EPT, Empathy for Pain task; FBT, False belief task; FH, Frith-Happé animations task; FIT, Facial Identification task; FPT, Faux paux test; G, Good; G1, group 1; G2, group 2; GRN-PPA, progranulin-associated aphasia; HC, Healthy Controls; IGT, Iowa Gambling Task; IRI, Interpersonal Reactivity Index; JBI, Joanna Briggs Institute Critical Evaluation Checklists; Le, Left; L, Low; Lo, Longitudinal; lvPPA, logopenic variant PPA; M, Moderate; MET, Multifaceted Empathy Test; mini-SEA, mini Social cognition and Emotion Assessment; N/A, not available; ND, neurodegenerative dementia; nfvPPA, Non fluent variant PPA; RMET, Reading the Mind in the Eyes Test; R, Right; SET, test Storey-based Empathy Task; SNQ, Social Norms Questionnaire; SP, Social Perception; svPPA, semantic variant PPA; TASIT, The Awareness of Social Inference Test; ToM, Theory of Mind; TRCT, The Referential Communication Task.