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. 2022 Apr 27;12:889159. doi: 10.3389/fonc.2022.889159

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Copyright © 2022 Long, Wang, Weng, Xiang and Sun

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of ECM1 expression in CRC tumors and cell lines. (A) ECM1 levels in CRC patient tumors and adjacent normal tissue samples were analyzed using the Oncomine database. (B) Representative IHC staining results for CRC patient tumor and paracancerous tissues. (C) ECM1 mRNA expression in CRC tumors and paracancerous tissues. (D) ECM1 protein levels in CRC tumors and paracancerous tissues. (E) ECM1 mRNA levels in CRC and colonic epithelial cell lines. (F) ECM1 protein levels in CRC (SW480, SW620, HT29, HCT116, HCT15) and colonic epithelial (NCM460) cell lines. Data are means ± SD (**P < 0.01, ***P < 0.001, ****P < 0.0001).