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ECM1 regulates signaling via the PI3K/AKT/GSK3β/Snail axis within CRC cells. Western blotting was used to assess AKT, p-AKT, GSK, pGSK3β, and Snail levels in CRC cells following (A, B) ECM1 knockdown or (C, D) ECM1 overexpression. Data are means ± SD (**P < 0.01, ***P< 0.001, ****P < 0.0001).
