(A) Relative miR-335-5p expression in HUVECs determined using RT-PCR assay (n=3, in all groups). (B) Relative SIRT7 expression in HUVECs determined using RT-PCR assay (n=3, in all groups). (C) Western blot assay on HUVECs for SIRT7 expression following SIRT7–siRNA transfection (n=3, in all groups). NS: non-significance, **P<0.01 versus the blank or control group, ***P<0.005 versus the blank or control group, ##P<0.01 versus the underlined group, ###P<0.005 versus the underlined group. All raw Western blots data of this article are presented in Supplementary Figure S4. Values of all groups followed a Gaussian distribution.