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. 2022 Apr 27;9:877975. doi: 10.3389/fnut.2022.877975

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Copyright © 2022 Zhou, Gao, Cao, Tian, Huang, Guo, Zhao, Hu, Liu and Guo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Multivariate analysis of the untargeted UHPLC-QTOF/MS metabolomics. The PCA score plots display the variance of positive (A) and negative (B) ions among TN, PF, and HS groups. The OPLS-DA score chart of serum metabolite analyzes the variance of positive (C) and negative (D) ions between the HS and TN groups, and the variance of positive (E) and negative (F) ions between the PF and TN groups.