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The effects of LPS challenge on the expression of brain-specific miRNAs in the mouse serum sEVs. RT-PCR assessed the expression of nine brain-specific miRNAs and three inflammatory miRNAs in the mouse serum sEVs. Data were expressed as the fold change ± SEM (n = 3) compared to normal control (NC). Statistical significance was determined by student t-test. ***p < 0.001.
