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. 2022 Apr 27;10:912133. doi: 10.3389/fbioe.2022.912133

FIGURE 1.

FIGURE 1

Inflammatory cells were enriched mainly in the reparative area sites of repair and their numbers gradually fell during progressive-stage to end-stage NONFH (A) Representative X-ray and femoral heads gross sample pictures from patients with NONFH. AP: anteroposterior, FL: frog-leg lateral (B) Representative images of HE-stained sections from patients with different types and stages of NONFH. SONFH, steroid-induced osteonecrosis of the femoral head; AONFH, alcohol-induced osteonecrosis of the femoral head; IONFH, idiopathic osteonecrosis of the femoral head. Scale bar, 2.5 mm (C–E) Representative images (C) and inflammatory cell quantification (D,E) in the reparative area in HE-stained tissues from patients with different types of progressive NONFH. Scale bar, 100 μm (F–H) Representative images (F) and inflammatory cell quantification (G,H) in necrotic areas of HE-stained tissues from patients with different types and stages of NONFH. *p < 0.05; **p < 0.01; ***p < 0.001.