Table 4.
The Common Genes, Proteins, Metabolites Changed in recurrent pregnancy loss patients compared with normal pregnancy females.
| Decidua | Villus | Blood | |
|---|---|---|---|
| The Common Genes with Differentially Methylated Regions | C2ORF54, TMEM161B, TBX3, SKI, TAL1, GPR137B, ITGA4 (54, 60) | CYP1A2, DEFB1, APC, AXL, CDKN1C, MEG3, PLAGL1 (77, 78) | Only One Reference (91) |
| The Common mRNAs | IFI44L, IFIT1, TNFRSF21, MMP26 (64, 73) | No Common mRNAs (82–84) | No Reference |
| The Common Proteins | ALB, NACA4P, KRT2, FARSA, CAT, TUBA8 (45, 70) | No Common Proteins (85, 86) | ITIH4, IGFBP4 (92, 93) |
| The Common metabolites | Only One Reference (72) | Only One Reference (87) | Only One Reference (94) |
Genomics data do not intersect and are therefore not represented in the Table 4 . There are many types of non-coding RNAs while few related transcriptomic studies, the sequencing results cannot be intersected. C2ORF54, chromosome 2 open reading frame 54; TMEM161B, transmembrane protein 161B; TBX3, T-box transcription factor 3; SKI, v-ski avian sarcoma viral oncogene homolog; TAL1, T-cell acute lymphocytic leukemia 1; GPR137B, G protein-coupled receptor 137B; ITGA4, integrin subunit alpha 4; APC, adenomatosis polyposis coli; CDKN1C, cyclin dependent kinase inhibitor 1C; MEG3, maternally expressed 3; PLAGL1, pleiomorphic adenoma gene-like 1; IFI44L, interferon induced protein 44 like; IFIT1, interferon induced protein with tetratricopeptide repeats 1; TNFRSF21, TNF receptor superfamily member 21; MMP26, matrix metallopeptidase 26; ALB, albumin; NACA4P, putative nascent polypeptide-associated complex subunit alpha-like protein; KRT2, type II cytoskeletal 2 epidermal; FARSA, phenylalanine–tRNA ligase alpha subunit; CAT, catalase; TUBA8, tubulin alpha-8 chain; ITIH4, inter-alpha-inhibitor heavy chain 4; IGFBP4, insulin-like growth factor-binding protein 4.