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. 2022 Apr 27;13:826198. doi: 10.3389/fimmu.2022.826198

Table 4.

The Common Genes, Proteins, Metabolites Changed in recurrent pregnancy loss patients compared with normal pregnancy females.

Decidua Villus Blood
The Common Genes with Differentially Methylated Regions C2ORF54, TMEM161B, TBX3, SKI, TAL1, GPR137B, ITGA4 (54, 60) CYP1A2, DEFB1, APC, AXL, CDKN1C, MEG3, PLAGL1 (77, 78) Only One Reference (91)
The Common mRNAs IFI44L, IFIT1, TNFRSF21, MMP26 (64, 73) No Common mRNAs (8284) No Reference
The Common Proteins ALB, NACA4P, KRT2, FARSA, CAT, TUBA8 (45, 70) No Common Proteins (85, 86) ITIH4, IGFBP4 (92, 93)
The Common metabolites Only One Reference (72) Only One Reference (87) Only One Reference (94)

Genomics data do not intersect and are therefore not represented in the Table 4 . There are many types of non-coding RNAs while few related transcriptomic studies, the sequencing results cannot be intersected. C2ORF54, chromosome 2 open reading frame 54; TMEM161B, transmembrane protein 161B; TBX3, T-box transcription factor 3; SKI, v-ski avian sarcoma viral oncogene homolog; TAL1, T-cell acute lymphocytic leukemia 1; GPR137B, G protein-coupled receptor 137B; ITGA4, integrin subunit alpha 4; APC, adenomatosis polyposis coli; CDKN1C, cyclin dependent kinase inhibitor 1C; MEG3, maternally expressed 3; PLAGL1, pleiomorphic adenoma gene-like 1; IFI44L, interferon induced protein 44 like; IFIT1, interferon induced protein with tetratricopeptide repeats 1; TNFRSF21, TNF receptor superfamily member 21; MMP26, matrix metallopeptidase 26; ALB, albumin; NACA4P, putative nascent polypeptide-associated complex subunit alpha-like protein; KRT2, type II cytoskeletal 2 epidermal; FARSA, phenylalanine–tRNA ligase alpha subunit; CAT, catalase; TUBA8, tubulin alpha-8 chain; ITIH4, inter-alpha-inhibitor heavy chain 4; IGFBP4, insulin-like growth factor-binding protein 4.