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. 2022 Apr 27;12:862211. doi: 10.3389/fcimb.2022.862211

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Copyright © 2022 Rojas, Grüttner, Ma’ayeh, Xu and Svärd

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Molecular function enrichment analysis of up-regulated human genes (more than two-fold) during Giardia infections of differentiated Caco-2 cells. Comparison of the top 10 gene ontology (GO) terms in molecular function in each of the different Giardia stage infections (trophozoite, cyst and encysting cells Caco-2 infections) and infection timepoints (1.5, 3, and 4.5 h post-infection). Circle size and color indicate the gene ratio (number of differentially expressed genes against the number of genes associated with a GO term) and their significance, respectively. GO, gene ontology; MF, molecular functions.