Table 1.
Genes related to metabolism over- or underexpressed in U87WT vs. U87Mut cells.
| Gene | OMIM | Gen name |
|---|---|---|
| Overexpressed in U87WT clone after 24 h of IGF1 stimulation | ||
| GAPDH | * 138400 | Glyceraldehyde-3-phosphate dehydrogenase |
| SLC2A11 | * 610367 | Solute carrier family 2 (facilitated glucose transporter), member 11 |
| LDHB | * 150100 | Lactate dehydrogenase B |
| LPIN1 | * 605518 | Lipin 1 |
| MDH1 | * 154200 | Malate dehydrogenase 1, NAD |
| LDHA | * 150000 | Lactate dehydrogenase A |
| PCK2 | * 614095 | Phosphoenolpyruvate carboxykinase 2 |
| IDH3A | * 601149 | Isocitrate dehydrogenase 3 (NAD+) alpha |
| PPAP2C | * 607126 | Phosphatidic acid phosphatase type 2C |
| Underexpressed in U87WT clone after 24 h of IGF1 stimulation | ||
| ACAT1 | * 607809 | Acetyl-CoA acetyltransferase 1 |
| ACSF3 | * 614245 | Acyl-CoA synthetase family member 3 |
| CPT1A | * 600528 | Carnitine palmitoyltransferase 1A |
| PDPR | * 617835 | Pyruvate dehydrogenase phosphatase regulatory subunit |
| SLC2A14 | * 611039 | Solute carrier family 2 (facilitated glucose transporter), member 14 |
| FABP5 | * 605168 | Fatty acid-binding protein 5 |
| AGPAT1 | * 603099 | 1-Acylglycerol-3-phosphate O-acyltransferase 1 |
| SLC16A3 | * 603877 | Solute carrier family 16 (monocarboxylate transporter), member 3 |
| PFKFB4 | * 605320 | 6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| FADS3 | * 606150 | Fatty acid desaturase 3 |
| LDHAL6A | * 618928 | Lactate dehydrogenase A-like 6A |
| ACSL6 | * 604443 | Acyl-CoA synthetase medium-chain family member 6 |
| ACSF2 | * 610465 | Acyl-CoA synthetase family member 2 |
| ACSL5 | * 605677 | Acyl-CoA synthetase long-chain family member 5 |
| PFKFB2 | * 171835 | 6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| GCK | * 138079 | Glucokinase |
| SPTLC3 | * 611120 | Serine palmitoyltransferase, long-chain-base subunit 3 |
| Overexpressed in U87WT clone in all conditions | ||
| CH25H | * 604551 | Cholesterol 25-hydroxylase |
| LPCAT3 | * 611950 | Lysophosphatidylcholine acyltransferase 3 |
| SREBF1 | * 184756 | Sterol regulatory element-binding transcription factor 1 |
| SOD2 | * 147460 | Superoxide dismutase 2, mitochondrial |
| SOD1 | * 147450 | Superoxide dismutase 1, soluble |
The numbers displayed in table 1 are OMIM numbers. An asterisk (*) before an entry number indicates a gene.