TABLE 2.
Insulin resistance parameters in children who were born very preterm and at term
| Very Preterm (n = 77) | Term (n = 43) | p value | |||
|---|---|---|---|---|---|
| Median [IQ] | Mean (SD) | Median [IQ] | Mean (SD) | ||
| Lipid profile | |||||
| Total cholesterol (mg/dl) | 148 [132–165] | 150 (24.8) | 157 [136–171] | 156.9 (26.1) | .216 a |
| TG (mg/dl) | 61[46–79] | 66.8 (30.8) | 57 [44–72] | 61.7 (25.9) | .356 |
| HDL‐C (mg/dl) | 54 [46–62] | 53.7 (11.0) | 58 [50–66] | 58.7 (10.6) | .019 a |
| LDL‐C (mg/dl) | 82 [69–97] | 83.7 (22.6) | 83 [71–94] | 85.8 (22.2) | .825 |
| VLDL‐C (mg/dl) | 12 [9−16] | 13.3 (6.2) | 11 [9–14] | 12.3 (5.1) | .407 |
| Insulin resistance indexes and metabolic syndrome score | |||||
| Glycaemia (mg/dl) | 84 [80–88] | 84 (6.8) | 84 [80–88] | 83 (7.4) | .928 |
| Insulin (μU/ml) | 4.7 [3.4–7.0] | 5.9 (3.7) | 5.1 [3.6–7.1] | 5.6 (2.9) | .907 |
| TG/HDL ratio | 1.06 [0.83–1.55] | 1.36 (0.9) | 0.88 [0.75–1.35] | 1.09 (0.49) | .116 |
| HOMA | 1.02 [0.68–1.56] | 1.26 (0.82) | 1.06 [0.7–1.55] | 1.18 (0.64) | .945 |
| QUICKI | 0.17 [0.16–0.18] | 0.17 (0.02) | 0.17 [0.16–0.18] | 0.17 (0.04) | .921 |
| PsiMS | 1.66 [1.38–1.87] | 1.69 (0.49) | 1.48 [1.24–1.73] | 1.50 (0.39) | .043 |
| Other biochemical variables | |||||
| GOT (IU/L) | 29[25–32] | 29.5 (5.4) | 28[25–30] | 30.0 (11.5) | .246 |
| GPT (IU/L) | 16[12–19] | 16.6 (6.2) | 15[12–18] | 18.3 (15.1) | .530 |
| Microalbumin/Cr (mg/g) | 8.6[5.4–23] | 19.2 (29.8) | 7.2[5.5–13.3] | 25.0 (71.5) | .425 |
Insulin (μU/ml) * 6.945 = pmol/L, glycaemia (mg/dl) * 0.0555 = mmol/L. For total, HDL, and LDL cholesterol (mg/dl) * 0.0259 = mmol/L; and for TG * 0.0113.
Abbreviation: HDL‐C, high‐density lipoprotein cholesterol; PsiMS, Pediatric siMS score; TG, triglyceride.
a
p value is from Mann–Whitney U test or independent samples t‐test.