FIGURE 5.

Effect of curcumin/cyclodextrin polymer (CUR/CDP) pretreatment on the activity of catalase (CAT) (a) and malondialdehyde (MDA) content (b) in LO2 cells treated with H₂O₂. LO2 cells were preincubated with CUR/CDP (10–40 µg/ml) for 12 h and then stimulated with H₂O₂ (700 µM) for additional 3 h. The intracellular MDA content and CAT activity were detected with spectrophotometry. p < 0.01 (**) or p < 0.05(*) means that columns between H₂O₂ group and CUR/CDP groups are significantly different. p < 0.01 (##) means that columns between control group and H₂O₂ group are significantly different