. 2022 Apr 27;9:852012. doi: 10.3389/fnut.2022.852012

Table 5.

Oxidation indexes (T-SOD, CAT, MDA, GSH, and ROS) in liver, kidney, brain tissue, and serum of SD rats.

	Tissue/serum	Group
		Normal group	Lead-induced group	EDTA group	L. fermentum SCHY34 group
T-SOD	Liver U/mgprot	253.78 ± 14.29^d	155.41 ± 10.76^a	182.33 ± 9.91^b	224.65 ± 10.37^c
	Kidney U/mgprot	111.95 ± 4.38^d	56.18 ± 2.56^a	86.21 ± 4.31^b	99.39 ± 3.68^c
	brain tissue U/mgprot	264.72 ± 7.26^d	94.59 ± 6.76^a	146.34 ± 8.43^b	200.75 ± 10.76^c
	Serum U/mlprot	409.48 ± 10.58^d	218.67 ± 7.29^a	338.45 ± 15.47^b	386.47 ± 3.85^c
CAT	Liver U/mgprot	52.48 ± 1.71^d	13.84 ± 0.79^a	30.76 ± 3.01^b	41.58 ± 1.78^c
	Kidney U/mgprot	12.79 ± 0.64^d	2.18 ± 0.30^a	4.16 ± 0.71^b	8.59 ± 0.45^c
	brain tissue U/mgprot	45.89 ± 1.96^d	18.15 ± 1.03^a	28.43 ± 1.61^b	35.97 ± 1.97^c
	Serum U/mlprot	37.81 ± 1.45^d	13.49 ± 1.48^a	25.49 ± 1.56^b	31.33 ± 1.72^c
GSH	Liver μmol/g	416.81 ± 14.56^d	206.81 ± 11.74^a	290.25 ± 18.65^b	352.24 ± 15.51^c
	Kidney μmol/g	291.46 ± 16.45^d	118.64 ± 15.71^a	186.93 ± 13.52^b	235.02 ± 15.23^c
	brain tissue μmol/g	354.32 ± 10.53^d	178.52 ± 17.10^a	221.85 ± 18.79^b	295.11 ± 10.25^c
	Serum μmol/l	286.57 ± 15.22^d	104.82 ± 14.67^a	195.64 ± 13.71^b	247.50 ± 11.63^c
MDA	Liver nmol/mgprot	1.11 ± 0.04^a	3.35 ± 0.20^d	2.87 ± 0.14^c	1.58 ± 0.19^b
	Kidney nmol/mgprot	0.57 ± 0.14^a	3.30 ± 0.54^d	2.16 ± 0.21^c	1.40 ± 0.17^b
	brain tissue nmol/mgprot	7.49 ± 0.45^a	28.56 ± 0.12^d	18.43 ± 0.25^c	12.71 ± 0.57^b
	Serum nmol/mlprot	1.45 ± 0.09^a	7.97 ± 0.53^d	5.36 ± 0.41^c	3.04 ± 0.30^b
ROS	Liver (×10⁴)	2.32 ± 0.19^a	6.41 ± 0.12^d	3.61 ± 0.17^c	2.88 ± 0.13^b
	Kidney (×10⁴)	1.94 ± 0.41^a	5.82 ± 0.21^d	6.57 ± 0.23^c	4.99 ± 0.17^b
	brain tissue (×10⁴)	0.94 ± 0.14^a	6.14 ± 0.32^d	3.87 ± 0.16^c	2.60 ± 0.37^b
	Serum (×10⁴)	2.74 ± 0.10^a	9.96 ± 0.39^d	6.68 ± 0.29^c	4.56 ± 0.26^b

Value presented are the mean ± standard deviation (n = 12/group).

^a−d

Mean values with different letters in the same row are significantly different (p < 0.05) according to Duncan's multiple range test. Lead-induced group: Rat free to drink 200 mg/L lead acetate solution every day; EDTA group: Rat free to drink 200 mg/L lead acetate solution every day and treated with 500 mg/kg (b.w) EDTA every day from 8 to 12 week; L. fermentum SCHY34 group: Rat free to drink 200 mg/L lead acetate solution every day and treated with 1.0 ×10⁹ CFU/kg (b.w) of L. fermentum SCHY34 every day.