Table 3. Causal inference results: MR results for biomarkers significantly associated with eGFR in cross-sectional analyses.
Protein biomarker exposure | Protein biomarker abbreviation | Kidney trait outcome | nsnp | β ± SE | p-value |
---|---|---|---|---|---|
Melanoma cell adhesion molecule | MCAM | eGFR (continuous) | 1 | -0.0111 ± 0.0027 | 5.11E-5 |
Epidermal growth factor containing fibulin-like extracellular matrix protein 1 | EFEMP1 | eGFR (continuous) | 2 | -0.0064 ± 0.0016 | 1.04E-4 |