Fig 4. Predicting behavioral response to a given target cue based on firing rate activity.

For a given target cue such as O3, this analysis sought to predict whether a lick or no lick response occurred based on activity preceding the target cue during the context and delay period. (A) Sliding window demonstrating the proportion of units that show discriminatory activity between the 2 context cues throughout the different periods in the trial, similar to Fig 3B and 3C. Red lines border context cue presentation, and black lines border target cue presentation. (B) Proportion of all units whose firing rate at a given point in the trial predicts the behavioral response to a given target cue above chance, according to a binomial regression. (C) Same as B, but using the firing rates of all units recorded for a mouse to generate a pseudo-ensemble prediction of the behavioral response for a given target cue. Each line denotes the prediction for a given mouse. Note, the variability across mice reflects the variability in single-unit context coding seen in Fig 3G. Data: https://gin.g-node.org/jgmaz/BiconditionalOdor.