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. 2022 Apr 27;12:874731. doi: 10.3389/fonc.2022.874731

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Copyright © 2022 Yang, Tan, Sun, Zeng and Pan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of prognostic LMGs in BC patients. (A) The somatic mutation frequency of LMGs in the TCGA-BRCA cohort. (B) The prevalent CNV frequency of LMGs in the TCGA-BRCA cohort. (C) Heatmap of differentially expressed genes among LMGs. (D) Volcano plot exhibiting DEGs in LMGs. (E) OS-related LMGs in TCGA-BRCA and METABRIC datasets, respectively. (F) The Veen diagram to detect 9 common prognostic LMGs. (G) The Circos plot illustrating the locations on chromosomes and expression levels of the 9 candidate LMGs. (H) The correlation matrix plot containing 9 prognostic LMGs.