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. 2022 May 11;8(19):eabi4529. doi: 10.1126/sciadv.abi4529

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Fig. 8. — (A) Box plots recapitulating the effect of cas and D overexpression (OE) or grh knockdown on the proportion of Imp⁺ tNBs. (B) Box plots recapitulating the effect of cas and D misexpression or grh knockdown on tumor growth. (C) Yellow dotted lines delineate poxⁿ>pros^RNAi and poxⁿ>pros^RNAi, grh^RNAi tumors in a larval VNC. Immunostaining against Cas indicate that Cas is up-regulated in poxⁿ>pros^RNAi, grh^RNAi tumors. Scale bars, 20 μm. All images are single confocal sections. (D) Immunostainings against Imp, Chinmo, and Syp in poxⁿ>pros^RNAi and poxⁿ>pros^RNAi, grh^RNAi tumors found in adult VNCs. GFP labels all tNBs. Scale bars, 50 μm.