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. 2022 May 4;2022:4269733. doi: 10.1155/2022/4269733

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Copyright © 2022 Zhenchong Li et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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(a) The ESTIMATE algorithm revealed that the MBOAT2 level was positively correlated with tumor purity (Cor = 0.37, P = 3.8e − 07) but negatively correlated with immune score (Cor = −0.38, P = 2.7e − 07). (b) The CIBERSORT algorithm revealed that MBOAT2 overexpression is remarkably connected to the low infiltration level of CD8+ T-cells in the TME of PC (Cor = −0.41, P = 2.0e − 06). (c) A correlation analysis between MBOAT2 level and immune-related terms from the ssGSEA analysis of the TCGA PC cohort (|Cor| > 0.30, P < 0.05). Spearman's correlation was performed in (a)–(c).