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Invalidation of dieckol and PGG as SARS-CoV-2 Mpro inhibitors and validation of PGG as a PLpro inhibitor. A Flip-GFP Mpro assay results of dieckol and PGG. GC376 was included as a positive control. B FRET assay results of PGG against SARS-CoV-2 Mpro, SARS-CoV-2 PLpro, SARS-CoV PLpro, and MERS-CoV PLpro. C Thermal shift assay characterization of the binding of PGG to SARS-CoV-2 PLpro. D Flip-GFP PLpro assay result of PGG. The results are mean ± standard deviation of two repeats
