Table 1.

Multi-omic tools used to study basidiomycetous SMs and their products in food and pharmaceutical industries

Product name/fungal sources	Key component of SMs	Mode of action and applications	Omic tool	References
SM of Pleurotus ostreatus	Resveratrol	Antioxidant	Genomics and metabolomics	Takahashi et al. (2020)
Nutrient of Dictyophora indusiata	Vitamin C	Antioxidant activity	Nuclear magnetic resonance spectroscopy	Liu et al. (2019)
Bitter tea powder from G. lucidum & L. edodes	Lentinan	Antitumor properties or immunostimulants	2-DE coupled with mass spectrometry	Chuang et al. (2009)
Low-density lipoprotein (LDL) drug from A. bisporus, C. cibarius, I. abadia, and L. edodes	Lovastatin	Lowers cholesterol level	RP-HPLC	Kała et al. (2020)
MycoNutri Cordyceps Organic from C. militaris	Cordycepin	Reducing the LDL level, total cholesterol, triglycerides, and hyperlipidemia	Genomics and NMR	Ashraf et al. (2020)
Sun mushroom from A. subrufescens	Polyphenols and polysaccharides	Decrease oxidative stress and prevent non-transmissible chronic diseases (NTCD)	HPLC-MS	Navegantes-Lima et al. (2020)
Niu-Chang-Chih from A. cinnamomea	Antcins	Treat various diseases such as diarrhea, abdominal pain, hypertension, and reduced prostate cancer	NMR, electron ionization mass spectrometry (EI-MS)	Kumar et al. (2020)
Caterpillar as a H. sinensis	Polysaccharides	Prebiotic and diabetic control	Next-generation sequencing technology	Takahashi et al. (2020)
Edible mushroom V. volvacea, P. geesteranum, H. erinaceus, and P. sapidus in China, East and Southeast Asia	Ergosterol class, ergosterol peroxide	Immunoregulation and antitumor effect	NMR-based metabolomics	Chen et al. (2020); Takahashi et al. (2020)
Fusarium venenatum by Quorn™ industry	Food supplements	Immunological action, antioxidant	Fermentation and transcriptomics	Meyer et al. (2020)