Table 1.
CTRL | DS | DS-CA | |
---|---|---|---|
N | 11 | 16 | 12 |
Axis 1 diagnosis | 0 | MDD (14); DD-NOS (2) | MDD (11); DD-NOS (1) |
Age (years) (P = 0.38) | 43.18 ± 7.11 | 46.63 ± 3.48 | 37.75 ± 3.10 |
Sex (M/F) | 9/2 | 14/2 | 9/3 |
PMI (h) (P = 0.74) | 35.95 ± 7.15 | 45.95 ± 8.06 | 40.92 ± 6.68 |
Tissue pH (P = 0.42) | 6.40 ± 0.09 | 6.52 ± 0.07 | 6.56 ± 0.08 |
Substance dependence | 0 | 6 | 5 |
Medication | 0 | SSRI (4); SNRI (1); TCA (1); Benzodiazepines (3); Antipsychotics (2); Antimanic (1) | SSRI (2); Benzodiazepines (2); Antipsychotics (1); Antimanic (1) |
Data represent mean ± SEM. P-values generated with one-way ANOVAs.
DD-NOS depressive disorder not otherwise specified, MDD major depressive disorder, PMI post-mortem interval, SNRI selective norepinephrine reuptake inhibitor, SSRI selective serotonin reuptake inhibitor, TCA tricyclic antidepressant.