Table 5.
Summary of serum biochemical test in 90-day repeated oral dose of BPF
| Group (mg/kg/day) | |||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sex: male | G1 (0) | G2 (2) | G3 (10) | G4 (50) | G5 (100) | G6 (200) | |||||||||||||||||||
| Main group | CHO1 (mg/dl) | 77 | ± | 15 | (10) | 67 | ± | 13 | (10) | 66 | ± | 10 | (10) | 54** | ± | 12 | (10) | 50** | ± | 11 | (10) | 35** | ± | 9 | (10) |
| HDL2 (mg/dl) | 22 | ± | 3 | (10) | 20 | ± | 3 | (10) | 20 | ± | 2 | (10) | 17** | ± | 3 | (10) | 16** | ± | 3 | (10) | 12** | ± | 3 | (10) | |
| LDL3 (mg/dl) | 7 | ± | 2 | (10) | 7 | ± | 2 | (10) | 6 | ± | 1 | (10) | 5** | ± | 1 | (10) | 4** | ± | 1 | (10) | 3** | ± | 1 | (10) | |
| ChE4 (U/l) | 247 | ± | 39 | (10) | 246 | ± | 46 | (10) | 257 | ± | 47 | (10) | 222 | ± | 78 | (10) | 204 | ± | 52 | (10) | 161** | ± | 29 | (10) | |
| Recovery group | CHO (mg/dl) | 74 | ± | 31 | (5) | 66 | ± | 9 | (5) | ||||||||||||||||
| HDL (mg/dl) | 18 | ± | 5 | (5) | 18 | ± | 2 | (5) | |||||||||||||||||
| LDL (mg/dl) | 8 | ± | 3 | (5) | 6 | ± | 2 | (5) | |||||||||||||||||
| ChE (U/l) | 166 | ± | 63 | (5) | 92* | ± | 19 | (5) | |||||||||||||||||
| Sex: female | G1 (0) | G2 (1) | G3 (5) | G4 (15) | G5 (30) | G6 (60) | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Main group | CHO (mg/dl) | 85 | ± | 15 | (10) | 84 | ± | 12 | (10) | 73** | ± | 9 | (10) | 60** | ± | 8 | (10) | 59** | ± | 11 | (10) | 49** | ± | 14 | (10) |
| HDL (mg/dl) | 26 | ± | 3 | (10) | 26 | ± | 3 | (10) | 24 | ± | 2 | (10) | 21* | ± | 3 | (10) | 21 | ± | 3 | (10) | 18* | ± | 6 | (10) | |
| LDL (mg/dl) | 5 | ± | 1 | (10) | 6 | ± | 1 | (10) | 5 | ± | 1 | (10) | 4** | ± | 1 | (10) | 4 | ± | 1 | (10) | 5 | ± | 1 | (10) | |
| ChE(U/l) | 2058 | ± | 570 | (10) | 2272 | ± | 501 | (10) | 2235 | ± | 527 | (10) | 1800 | ± | 484 | (10) | 1798 | ± | 318 | (10) | 1676 | ± | 266 | (10) | |
| Recovery group | CHO (mg/dl) | 108 | ± | 28 | (5) | 111 | ± | 16 | (5) | ||||||||||||||||
| HDL (mg/dl) | 28 | ± | 6 | (5) | 30 | ± | 3 | (5) | |||||||||||||||||
| LDL (mg/dl) | 7 | ± | 2 | (5) | 5 | ± | 1 | (5) | |||||||||||||||||
| ChE (U/l) | 990 | ± | 286 | (5) | 947 | ± | 269 | (5) | |||||||||||||||||
Mean ± S.D (number of animals). 1: Total cholesterol, 2: high-density lipoproteins, 3: low-density lipoproteins, 4: cholinesterase
**Significant difference compared with control group value, p < 0.01, *Significant difference compared with control group value, p < 0.05