Table 1.
Patient-specific and surgery-specific characteristics of obese and non-obese patients
| Characteristics | Population | ||
|---|---|---|---|
| Full (n = 30) | Obese (n = 15) | Non-obese (n = 15) | |
| Sex, female | 26 (86.7) | 13 (86.7) | 13 (86.7) |
| Age, years | 51.5 (30.0–65.0) | 52.0 (30.0–65.0) | 50.0 (31.0–64.0) |
| Total body weight [kg] | 101 (52.0–230) | 121 (96.0–230) | 65.0 (52.0–84.0) |
| BMI [kg/m2] | 32.6 (20.5–81.5) | 44.7 (38.1–81.5) | 23.6 (20.5–27.1) |
| ABW [kg] | 70.5 (51.4–128) | 81.6 (66.0–128) | 60.3 (51.4–72.8) |
| Serum creatinine concentration [µmol/L] | 63.0 (40.6–127) | 63.0 (40.6–103) | 66.4 (51.8–127) |
| CLCRCG_ABW [mL/min] | 87.9 (51.3–188) | 99.4 (51.3–188) | 76.0 (53.6–136) |
| Anesthesia duration [h] | 4.22 (2.38–8.63) | 4.08 (2.97–5.63) | 4.78 (2.38–8.63) |
| MAPa [mmHg] | 75.4 (48.3–130) | 76.7 (48.3–130) | 72.5 (53.3–105) |
| Intra-anesthetic | 72.7 (50.0–105) | 72.5 (50.0–102) | 75.0 (53.3–105) |
| Post-anesthetic | 85.0 (48.3–130) | 96.7 (48.3–130) | 81.2 (58.3–105) |
Data are presented as median (range) or count (%)
ABW adjusted body weight, BMI body mass index, CLCRCG_ABW creatinine clearance calculated via Cockcroft–Gault using ABW, MAP mean arterial pressure (summary statistics computed based on individual median of observed intra-anesthetic data and post-anesthetic data, respectively)
aTime-varying parameter