Table 16.

Existing cancer potency estimates for bromate based on male F344 rat renal tumors

Cancer potency [mg bromate/kg bw/d]	Type	Species, sex	Study	Extrapolation method	Source
0.59	hLEDL10a	Male F344 rat	DeAngelo et al. (1998)	Multistage Weibull time-to-tumor model, scaling	US EPA (2001)
0.96	hLEDL10			Multistage Weibull time-to-tumor model, scaling	OEHHA (2009)
1.00	hBMDL10b			Multistage Weibull time-to-tumor model, PBPK, scaling	Health Canada (2018)

^aLower-bound estimate of the average lifetime dose associated with a ten percent human cancer risk, lower 95th percentile

^bLower 90% confidence limit of the benchmark doses for a 10% human cancer response