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. 2022 May 11;12:7778. doi: 10.1038/s41598-022-12034-6

Table 3.

Mortality risk associated with late non-fasting plasma glucose (dichotomous) in 5564 participants, stratified by HbA1c.

HbA1c CVD mortality All-cause mortality
HRa (95% CI) P value HRa (95% CI) P value
Plasma glucose ≥ 105 vs < 105 mg/dL
< 5.7% 2.61 (1.99–3.44) < 0.001 1.22 (1.01–1.47) 0.037
5.7%-6.4% 1.48 (1.05–2.07) 0.023 1.37 (1.12–1.68) 0.002
≥ 6.5% 1.21 (0.71–2.04) 0.488 1.13 (0.84–1.52) 0.422
Plasma glucose ≥ 110 vs < 110 mg/dL
< 5.7% 2.11 (1.51–2.94) < 0.001 1.20 (0.95–1.53) 0.131
5.7%-6.4% 1.64 (1.08–2.50) 0.020 1.55 (1.21–1.99) 0.001
≥ 6.5% 0.95 (0.58–1.57) 0.845 1.01 (0.76–1.34) 0.945
Plasma glucose ≥ 115 vs < 115 mg/dL
< 5.7% 3.50 (2.28–5.38) < 0.001 1.58 (1.14–2.19) 0.006
5.7%-6.4% 1.82 (1.08–3.07) 0.024 1.74 (1.29–2.37) < 0.001
≥ 6.5% 0.91 (0.56–1.47) 0.688 1.06 (0.80–1.40) 0.677

CI, confidence interval; CVD, cardiovascular disease; HbA1c, hemoglobin A1c; HR, hazard ratio.

aAdjusted for age, sex, ethnicity, obesity, education, poverty-income ratio, survey period, physical activity, alcohol consumption, smoking status, self-reported hypertension, self-reported hypercholesterolemia, and natural log-transformed HbA1c.